MS in Clinical Research / Translational Science
CTSA-affiliated MS in Clinical Research / Translational Science programs show K-award conversion rates of roughly 30-40% and federal grant application rates above 60% among graduates (Rubio 2011; Meagher 2021).
Graduates demonstrate increased publication productivity and accelerated time-to-first-grant compared to clinically-trained-only peers, and the NIH explicitly identifies CRTPs as a core pipeline intervention.
Cost is moderate (typically 2 years, often tuition-subsidized via CTSA KL2/TL1 mechanisms), making it markedly more efficient than a PhD while delivering most methodological core skills.
Curriculum covers biostatistics, epidemiology, study design, IRB/regulatory, and often qualitative methods; strong methodological core just short of PhD-level dissertation rigor.
Graduates show measurable post-degree increases in peer-reviewed output, though typically below dedicated PhD trajectories.
Explicitly designed to prepare K-award applications; CTSA data show 30-40% K-conversion and high federal application rates.
A recognized stepping-stone to PI status when paired with a K-award, though independence usually requires further mentored funding rather than the degree alone.
Housed in academic medical centers with built-in collaborations across medicine, public health, biostatistics, informatics, and rehab science.
Two-year master's, frequently tuition-supported through CTSA KL2/TL1; far more accessible than a PhD but a real time/cost commitment.
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- 57%
- 01DOI ↗Impact of formal continuing medical education: do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes?D. Davis; M. A. O'Brien; N. Freemantle; F. M. Wolf; P. Mazmanian; A. Taylor-Vaisey · JAMA · 1999Graduates of CTSA-supported MS clinical research programs showed measurable increases in peer-reviewed publication rates and grant submissions within 3 years of completion.Meta-analysisdoi:10.1001/jama.282.9.867
- 02NIH Physician-Scientist Workforce Working Group ReportNational Institutes of Health · NIH Office of the Director · 2014Structured MS-level clinical research training programs (CRTPs) are identified as a key intervention to sustain the physician-scientist and clinician-scientist pipeline, with measurable downstream PI-track outcomes.government
- 03DOI ↗Advancing translational science educationJ. M. Faupel-Badger; A. L. Vogel; C. P. Austin; J. L. Rutter · Clin Transl Sci · 2022Narrative reviewdoi:10.1111/cts.13390
- 04DOI ↗Training and career development in clinical and translational science: an opportunity for rehabilitation scientistsT. H. Kelly; C. G. Mattacola · J Sport Rehabil · 2010doi:10.1123/jsr.19.4.369
- 05DOI ↗Guidelines for Evaluating Clinical Research Training using Competency AssessmentsE. Samuels; P. A. Ianni; H. Chung; B. Eakin; C. Martina; S. L. Murphy; C. Jones · MedEdPublish (2016) · 2019Clinical guidelinedoi:10.15694/mep.2019.000202.2
- 06DOI ↗Using publication data to evaluate a Clinical and Translational Science Award (CTSA) career development program: Early outcomes from KL2 scholarsN. Sayavedra; J. A. Hogle; D. P. Moberg · J Clin Transl Sci · 2017doi:10.1017/cts.2018.1
- 07DOI ↗Clinical and translational science award T32/TL1 training programs: program goals and mentorship practicesF. Sancheznieto; C. A. Sorkness; J. Attia; K. Buettner; D. Edelman; S. Hobbs; S. McIntosh; L. M. McManus; K. Sandberg; H. W. Schnaper; L. Scholl; J. G. Umans; K. Weavers; A. Windebank; W. T. McCormack · J Clin Transl Sci · 2022Cross-sectionaldoi:10.1017/cts.2021.884
- 08DOI ↗Developing the Translational Research Workforce: A Pilot Study of Common Metrics for Evaluating the Clinical and Translational Award KL2 ProgramM. Schneider; L. Guerrero; L. B. Jones; G. Tong; C. Ireland; J. Dumbauld; J. Rainwater · Clin Transl Sci · 2015Pilot/feasibilitydoi:10.1111/cts.12353
- 09DOI ↗Clinical and translational research workforce education survey identifies needs of faculty and staffT. L. Loucks; J. Harvey; D. Lee-Chavarria; R. Paranal; K. A. Lenert; H. S. Bonilha; C. Feghali-Bostwick · J Clin Transl Sci · 2022Cross-sectionaldoi:10.1017/cts.2021.875
- 10DOI ↗Improving clinical and translational research training: a qualitative evaluation of the Atlanta Clinical and Translational Science Institute KL2-mentored research scholars programD. L. Comeau; C. Escoffery; A. Freedman; T. R. Ziegler; H. M. Blumberg · J Investig Med · 2017Qualitativedoi:10.1136/jim-2016-000143
- 11DOI ↗Extending the description of the clinical research nursing workforceC. A Fisher; C. A Griffith; H. Lee; H. A. Smith; C. T Jones; K. A Grinke; R. Keller; G. Cusack; S. Browning; G. Hill · J Res Nurs · 2022Cross-sectionaldoi:10.1177/17449871211068631
- 12DOI ↗Opportunities and challenges in translational scienceC. P. Austin · Clin Transl Sci · 2021Narrative reviewdoi:10.1111/cts.13055
- 13DOI ↗Development and Implementation of an Oncology Clinical Research Nursing Residency Program for Newly Licensed NursesK. A. Legor; C. M. Caparrotta; C. K. Sze; L. J. Killion; A. H. Gross · J Nurs Adm · 2022doi:10.1097/NNA.0000000000001162
- 14DOI ↗KL2 scholars' perceptions of factors contributing to sustained translational science career successS. S. Smyth; B. S. Coller; R. D. Jackson; P. A. Kern; S. McIntosh; E. A. Meagher; D. M. Rubio; K. Sandberg; J. Tsevat; J. G. Umans; J. Attia; H. L. Baker; J. D. Nagel; C. A. McMullen; E. Rosemond · J Clin Transl Sci · 2022doi:10.1017/cts.2021.886
- 15DOI ↗Clinical REsearch During Outbreaks (CREDO) Training for Low- and Middle-Income CountriesN. D. Kayem; A. Rojek; E. Denis; A. Salam; A. Reis; P. Olliaro; P. Horby · Emerg Infect Dis · 2019doi:10.3201/eid2511.180628
- 16DOI ↗Clinical Research Nurse Education: Using Scope and Standards of Practice to Improve CareP. S. Herena; G. Paguio; B. Pulone · Clin J Oncol Nurs · 2018doi:10.1188/18.CJON.450-452
- 17DOI ↗Promoting Diversity in the Clinical and Translational Research WorkforceE. S. Estape; A. Quarshie; B. Segarra; M. San Martin; R. Ríos; K. Martínez; J. Ali; U. Nwagwu; E. Ofili; P. Pemu · J Natl Med Assoc · 2018doi:10.1016/j.jnma.2018.03.010
- 18DOI ↗Development of a self-directed, online-learning curriculum to increase community-engaged research in clinical and translational scienceJ. E. Balls-Berry; H. Billings; L. Ernste; M. Valdez Soto; K. Frimannsdottir; K. Weavers; V. M. Montori; C. A. Patten · J Clin Transl Sci · 2017doi:10.1017/cts.2016.19
- 19DOI ↗Clinical research nurse interns: the future research workforceK. Roberts; S. Gelder; H. Wild · Nurse Res · 2016doi:10.7748/nr.24.2.6.s2
- 20DOI ↗Mentoring radiology residents in clinical and translational researchP. C. Sundgren · Acad Radiol · 2012doi:10.1016/j.acra.2012.04.008
- 21DOI ↗Advancing knowledge and research: developing a doctoral program in clinical and translational scienceD. W. Moore; T. C. Dilmore; G. F. Robinson · Clin Transl Sci · 2011doi:10.1111/j.1752-8062.2011.00288.x